Vaccines: New Generation Immunological Adjuvants by Gregory Gregoriadis (English

Description: Vaccines by Gregory Gregoriadis, Brenda McCormack, Anthony C. Allison This book contains the proceedings of the 4th NATO Advanced Studies Institute (ASI) "Vaccines: New Generation Immunological Adjuvants" held at Cape Sounion Beach, Greece, during 24 June -5 . FORMAT Paperback LANGUAGE English CONDITION Brand New Publisher Description During the last decade or so vaccine development has been facilitated by rapid advances in molecular and cell biology. These have laid the foundations of a new generation of vaccines exemplified by subunit vaccines produced through gene cloning and by synthetic peptides mimicking small regions of proteins on the outer coat of viruses. Such peptide~ are capable of eliciting virus-neutralizing antibodies. Unfortunately, subunit and peptide vaccines are only weakly or non immunogenic in the absence of immunological adjuvants that are known to augment specific cell-mediated immune responses to the antigens and to promote the formation of protective antibodies. This book contains the proceedings of the 4th NATO Advanced Studies Institute (ASI) "Vaccines: New Generation Immunological Adjuvants" held at Cape Sounion Beach, Greece, during 24 June -5 . July 1994 and deals in depth with both theoretical and practical aspects of vaccinology. These include the role of antigen presenting cells in the induction of immune responses. immunopotentiation by a variety of new generation immunological adjuvants and vaccine carriers. and recent advances and perspectives in experimental vaccines as well as vaccinatioll with nucleic acids. We express our appreciation to Dr. K. Dalsgaard and Dr. J. L. Virelizier for their cooperatioll in planning the ASI and to Mrs. Concha Pening for her excellent production of the manuscripts. The ASI was held under the sponsorship of NATO Scientific Affairs Division and generously co-sponsored by SmithKline Beecham Pharmaceuticals (Philadelphia). Table of Contents Adjuvants for new and improved vaccines.- Liposome mediated immunopotentiation and immunomodulation.- Quil A, anti-carbohydrate antibody specificity and biological function.- Vaccine adjuvants based on gamma inulin.- Interleukin-2 as a co-adjuvant for liposomal tetanus toxoid.- Design of vaccines for the induction of antibody responses in Th-cell deficient individuals.- Strategies for the stimulation of Th cell subsets.- Feline immunodeficiency virus as a vaccine model.- Rational design of vaccine molecules to prevent pertussis.- Multicomponent viral vaccines and their use as immunogen delivery systems.- Vaccines against HPV of the uterine cervix: Problems in clinical applicability.- Local chemotherapy of lymph node metastases: Optimization of targeting accuracy.- Synthetic peptide vaccines: Success at last.- Peptide vaccines: New approaches to immunopotentiation.- Genetic restriction of responses to peptide antigens.- DNA-based immunization: Prospects for a hepatitis B vaccine.- Characterization of immune responses elicited by an experimental facilitated-DNA vaccine for human immunodeficiency virus type-1 (HIV-1).- Recombinant self-replicating RNA vaccines. Promotional Springer Book Archives Long Description During the last decade or so vaccine development has been facilitated by rapid advances in molecular and cell biology. These have laid the foundations of a new generation of vaccines exemplified by subunit vaccines produced through gene cloning and by synthetic peptides mimicking small regions of proteins on the outer coat of viruses. Such peptide~ are capable of eliciting virus-neutralizing antibodies. Unfortunately, subunit and peptide vaccines are only weakly or non immunogenic in the absence of immunological adjuvants that are known to augment specific cell-mediated immune responses to the antigens and to promote the formation of protective antibodies. This book contains the proceedings of the 4th NATO Advanced Studies Institute (ASI) "Vaccines: New Generation Immunological Adjuvants" held at Cape Sounion Beach, Greece, during 24 June -5 . July 1994 and deals in depth with both theoretical and practical aspects of vaccinology. These include the role of antigen presenting cells in the induction of immune responses. immunopotentiation by a variety of new generation immunological adjuvants and vaccine carriers. and recent advances and perspectives in experimental vaccines as well as vaccinatioll with nucleic acids. We express our appreciation to Dr. K. Dalsgaard and Dr. J. L. Virelizier for their cooperatioll in planning the ASI and to Mrs. Concha Pening for her excellent production of the manuscripts. The ASI was held under the sponsorship of NATO Scientific Affairs Division and generously co-sponsored by SmithKline Beecham Pharmaceuticals (Philadelphia). Details ISBN1461380146 ISBN-10 1461380146 ISBN-13 9781461380146 Format Paperback Imprint Springer-Verlag New York Inc. Subtitle New Generation Immunological Adjuvants Place of Publication New York, NY Country of Publication United States Edited by Anthony C. Allison DEWEY 615.372 Birth 1925 Year 2011 Publication Date 2011-09-16 Short Title VACCINES 1995/E Language English Media Book Illustrations VIII, 192 p. Pages 192 DOI 10.1007/978-1-4613-0357-2 Series Number 282 AU Release Date 2011-09-16 NZ Release Date 2011-09-16 US Release Date 2011-09-16 UK Release Date 2011-09-16 Author Anthony C. Allison Publisher Springer-Verlag New York Inc. Edition Description Softcover reprint of the original 1st ed. 1995 Series NATO Science Series A: Alternative 9780306452833 Audience Professional & Vocational We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:96352469;

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