Description: The Extracellular Matrix: an Overview Please note: this item is printed on demand and will take extra time before it can be dispatched to you (up to 20 working days). Author(s): Robert Mecham Format: Hardback Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG, Germany Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K ISBN-13: 9783642165542, 978-3642165542 Synopsis Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series ?Biology of Extracellular Matrix? provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment.? Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.
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Book Title: The Extracellular Matrix: an Overview
Number of Pages: 426 Pages
Publication Name: The Extracellular Matrix: an Overview
Language: English
Publisher: Springer-Verlag Berlin AND Heidelberg Gmbh & Co. KG
Item Height: 235 mm
Subject: Medicine, Chemistry, Biology
Publication Year: 2011
Type: Textbook
Item Weight: 903 g
Author: Robert Mecham
Item Width: 155 mm
Series: Biology of Extracellular Matrix
Format: Hardcover