Description: Sequential Experimentation in Clinical Trials : Design and Analysis, Hardcover by Bartroff, Jay; Lai, Tze Leung; Shih, Mei-chiung, ISBN 1461461138, ISBN-13 9781461461135, Brand New, Free shipping in the US Sequential Experimentation in Clinical Trials: Design and Analysis is developed from decades of work in research groups, statistical pedagogy, and workshop participation. Different parts of th can be used for short courses on clinical trials, translational medical research, and sequential experimentation. The authors have successfully used th to teach innovative clinical trial designs and statistical methods for Statistics . students at Stanford University. There are additional online supplements for th that include chapter-specific exercises and information. Sequential Experimentation in Clinical Trials: Design and Analysis covers the much broader subject of sequential experimentation that includes group sequential and adaptive designs of Phase II and III clinical trials, which have attracted much attention in the past three decades. In particular, the broad scope of design and analysis problems in sequential experimentation clearly requires a wide range of statistical methods and models from nonlinear regression analysis, experimental design, dynamic programming, survival analysis, resampling, and likelihood and Bayesian inference. The background material in these building blocks is summarized in Chapter 2 and Chapter 3 and certain sections in Chapter 6 and Chapter 7. Besides group sequential tests and adaptive designs, th also introduces sequential change-point detection methods in Chapter 5 in connection with pharmacovigilance and public health surveillance. Together with dynamic programming and approximate dynamic programming in Chapter 3, th therefore covers all basic topics for a graduate course in sequential analysis designs.
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Book Title: Sequential Experimentation in Clinical Trials : Design and Analys
Number of Pages: Xvi, 240 Pages
Language: English
Publication Name: Sequential Experimentation in Clinical Trials : Design and Analysis
Publisher: Springer New York
Publication Year: 2012
Item Height: 0.2 in
Subject: Clinical Medicine, Biostatistics, Probability & Statistics / General
Type: Textbook
Item Weight: 179.5 Oz
Subject Area: Mathematics, Medical
Item Length: 9.3 in
Author: Mei-Chiung Shih, Tze Leung Lai, Jay Bartroff
Series: Springer Series in Statistics Ser.
Item Width: 6.1 in
Format: Hardcover
