Description: Neurofibromatosis Type 1 Please note: this item is printed on demand and will take extra time before it can be dispatched to you (up to 20 working days). Molecular and Cellular Biology Author(s): Meena Upadhyaya, David N Cooper Format: Hardback Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG, Germany Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K ISBN-13: 9783642328633, 978-3642328633 Synopsis Neurofibromatosis type 1 (NF1), caused by mutational inactivation of the NF1 tumour suppressor gene, is one of the most common dominantly inherited human disorders, affecting 1 in 3000 individuals worldwide. This book presents in concise fashion, but as comprehensively as possible, our current state of knowledge on the molecular genetics, molecular biology and cellular biology of this tumour predisposition syndrome. Written by internationally recognized experts in the field, the 44 chapters that constitute this edited volume provide the reader with a broad overview of the clinical features of the disease, the structure and expression of the NF1 gene, its germ line and somatic mutational spectra and genotype-phenotype relationships, the structure and function of its protein product (neurofibromin), NF1 modifying loci, the molecular pathology of NF1-associated tumours, animal models of the disease, psycho-social aspects and future prospects for therapeutic treatment.
Price: 143.78 GBP
Location: Aldershot
End Time: 2024-11-27T12:01:56.000Z
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Book Title: Neurofibromatosis Type 1
Number of Pages: 717 Pages
Language: English
Publication Name: Neurofibromatosis Type 1: Molecular and Cellular Biology
Publisher: Springer-Verlag Berlin AND Heidelberg Gmbh & Co. KG
Publication Year: 2013
Subject: Medicine, Biology
Item Height: 235 mm
Item Weight: 1262 g
Type: Textbook
Author: David N Cooper, Meena Upadhyaya
Item Width: 155 mm
Format: Hardcover
