Neuroblastoma: Diagnosis, Therapy, and Prognosis by M.A. Hayat (English) Hardcov

Description: Neuroblastoma by M.A. Hayat Introduction of new technologies and their applications to neuroblastoma diagnosis, treatment, and therapy assessment are explained. Targets for therapeutic intervention in neuroblastoma are identified, including targeting multidrug resistance in this cancer. FORMAT Hardcover LANGUAGE English CONDITION Brand New Publisher Description Introduction of new technologies and their applications to neuroblastoma diagnosis, treatment, and therapy assessment are explained. Role of molecular ghenetics in diagnosis and therapy for neuroblastoma patients is detailed. Molecular detection of minimal residual neuroblastoma is described. Magnetic resonance imaging and spectroscopy are detailed for diagnosing this solid, extracranial cancer. Targets for therapeutic intervention in neuroblastoma are identified, including targeting multidrug resistance in this cancer. Ornithine decarboxylase and polyamines are novel targets for therapeutic intervention. The effectiveness of chemotherapy with oral irinotecan and temozolomide is explained. The role of transcription factors (GATA) in neuroblastoma pregression is also included. Notes Children with cancerPediatric physiciansResearchers in the field of pediatric cancerScientists involved in the development of cancer drugs Back Cover Introduction of new technologies and their applications to neuroblastoma diagnosis, treatment, and therapy assessment are explained. Role of molecular ghenetics in diagnosis and therapy for neuroblastoma patients is detailed. Molecular detection of minimal residual neuroblastoma is described. Magnetic resonance imaging and spectroscopy are detailed for diagnosing this solid, extracranial cancer. Targets for therapeutic intervention in neuroblastoma are identified, including targeting multidrug resistance in this cancer. Ornithine decarboxylase and polyamines are novel targets for therapeutic intervention. The effectiveness of chemotherapy with oral irinotecan and temozolomide is explained. The role of transcription factors (GATA) in neuroblastoma pregression is also included. Table of Contents Preface.-1. Introduction. I Diagnosis and biomarkers.-2. Pediatric cns neuroblastoma: magnetic resonance imaging and spectroscopy.-3. Pediatric neuroblastoma-associated opsoclonus-myoclonus-ataxia syndrome: early diagnosis.-4. Neuroblastoma mouse model.-5. Orbital metastasis in neuroblastoma patients.-6. Pediatric neuroblastoma: molecular detection of minimal residual disease.-7. A comprehensive tissue microarray-based fish screen of alk gene in neuroblastomas. II Therapy.-8. Neuroblastoma: triptolide therapy.-9. Neuroblastoma: ornithine decarboxylase and polyamines are novel targets for therapeutic intervention.-10. Neuroblastoma: antibody-based immunotherapy.-11. Targeting multidrug resistance in neuroblastoma.-12. Neuroblastoma: perspectives for the use of il-21 in immunotherapy.-13. Neuroblastoma: role of hypoxia and hypoxia inducible factors in tumor progression.-14. Neuroblastoma: role of gata transcription factors.-15. Neuroblastoma: role of mycn/bmil pathway in neuroblastoma.-16. Neuroblastoma: role of clusterin as a tumor suppressor gene.-17. Refractory neuroblastoma cells: statins target atp binding cassette-transporters.-18. Neuroblastoma: dosimetry for mibg therapies.-19. Advanced neuroblastoma: role of alk mutations.-20. Pediatric neuroblastoma: treatment with oral irinotecan and temozolomide. III Prognosis.-21. Genomic profiling of neuroblastoma tumors- prognostic impact of genomic aberrations.-22. Neuroblastoma patients: plasma growth factor mildkine as a prognostic growth factor.-23. Pediatric neuroblastoma: role of tgfbi (keratoepithelin).-24. Role of bone marrow infiltration detected by sensitive methods in patients with localized neuroblastoma. Index Feature Children with cancer Pediatric physicians Researchers in the field of pediatric cancer Scientists involved in the development of cancer drugs Details ISBN9400724179 Publisher Springer Series Pediatric Cancer Year 2011 ISBN-10 9400724179 ISBN-13 9789400724174 Format Hardcover Imprint Springer Place of Publication Dordrecht Country of Publication Netherlands DEWEY 618.929948 Language English Media Book Series Number 1 Subtitle Diagnosis, Therapy, and Prognosis Short Title NEUROBLASTOMA 2012/E Pages 262 Edition 2012th Illustrations XVIII, 262 p. DOI 10.1007/978-94-007-2418-1 Publication Date 2011-11-03 Author M.A. Hayat Edited by M.A. Hayat Edition Description 2012 ed. Alternative 9789401779098 Audience Professional & Vocational We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:96369100;

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