mRNA Metabolism & Post-Transcriptional Gene Regulation by Joe B. Harford (Englis

Description: mRNA Metabolism & Post-Transcriptional Gene Regulation by Joe B. Harford, David R. Morris Post-transcriptional reactions have been implicated in a number of clinical conditions (e.g. lupus, and rheumatoid arthritis), and regulatory mechanisms are the target of potential therapeutic strategies. This book provides a comprehensive overview of the various modes of gene regulation that exist post-transcriptionally. FORMAT Paperback LANGUAGE English CONDITION Brand New Publisher Description mRNA METABOLISM & POST-TRANSCRIPTIONAL GENE REGULATION Edited by Joe B. Harford and David R. Morris Gene expression is a process that begins with the transcription ofDNA to an RNA messenger (mRNA), which is then translated into aprotein. Historically, attention has been focused on the regulationof RNA synthesis (transcription); however, there is a growingrecognition of and appreciation for the importance of the manyregulatory mechanisms that take place after RNA synthesis has beencompleted. mRNA Metabolism and Post-Transcriptional Gene Regulation is thefirst comprehensive overview of the various modes of generegulation that exist post-transcriptionally. Collecting studies bysome of the top researchers in the field, this volume provides bothan up-to-date review of the complex "life" of an mRNA molecule andan introduction to current work on the diversity of mechanisms ofpost-transcriptional reactions. Topics covered include: * RNA structure * Mammalian RNA editing * RNA export from the nucleus * The fundamentals of translation initiation * Control of mRNA decay in plants * mRNA metabolism and cancer * Control of mRNA stability during herpes simplex virus infection * Regulation of mRNA expression in HIV-1 and other complexretroviruses * Nucleases * RNA localization A timely contribution to the understanding of genetic regulatorymechanisms, mRNA Metabolism and Post-Transcriptional GeneRegulation provides a basis from which potential therapeuticstrategies may be developed. This book will be of vital interest tocell and molecular biologists at all levels, from graduate studentsto senior investigators, clinical researchers, and professionals inthe pharmaceutical and biotechnology industries. Back Cover mRNA METABOLISM & POST-TRANSCRIPTIONAL GENE REGULATION Edited by Joe B. Harford and David R. Morris Gene expression is a process that begins with the transcription of DNA to an RNA messenger (mRNA), which is then translated into a protein. Historically, attention has been focused on the regulation of RNA synthesis (transcription); however, there is a growing recognition of and appreciation for the importance of the many regulatory mechanisms that take place after RNA synthesis has been completed. mRNA Metabolism and Post-Transcriptional Gene Regulation is the first comprehensive overview of the various modes of gene regulation that exist post-transcriptionally. Collecting studies by some of the top researchers in the field, this volume provides both an up-to-date review of the complex "life" of an mRNA molecule and an introduction to current work on the diversity of mechanisms of post-transcriptional reactions. Topics covered include: RNA structure Mammalian RNA editing RNA export from the nucleus The fundamentals of translation initiation Control of mRNA decay in plants mRNA metabolism and cancer Control of mRNA stability during herpes simplex virus infection Regulation of mRNA expression in HIV-1 and other complex retroviruses Nucleases RNA localization A timely contribution to the understanding of genetic regulatory mechanisms, mRNA Metabolism and Post-Transcriptional Gene Regulation provides a basis from which potential therapeutic strategies may be developed. This book will be of vital interest to cell and molecular biologists at all levels, from graduate students to senior investigators, clinical researchers, and professionals in the pharmaceutical and biotechnology industries. Flap mRNA METABOLISM & POST-TRANSCRIPTIONAL GENE REGULATION Edited by Joe B. Harford and David R. Morris Gene expression is a process that begins with the transcription of DNA to an RNA messenger (mRNA), which is then translated into a protein. Historically, attention has been focused on the regulation of RNA synthesis (transcription); however, there is a growing recognition of and appreciation for the importance of the many regulatory mechanisms that take place after RNA synthesis has been completed. mRNA Metabolism and Post-Transcriptional Gene Regulation is the first comprehensive overview of the various modes of gene regulation that exist post-transcriptionally. Collecting studies by some of the top researchers in the field, this volume provides both an up-to-date review of the complex "life" of an mRNA molecule and an introduction to current work on the diversity of mechanisms of post-transcriptional reactions. Topics covered include: RNA structure Mammalian RNA editing RNA export from the nucleus The fundamentals of translation initiation Control of mRNA decay in plants mRNA metabolism and cancer Control of mRNA stability during herpes simplex virus infection Regulation of mRNA expression in HIV-1 and other complex retroviruses Nucleases RNA localization A timely contribution to the understanding of genetic regulatory mechanisms, mRNA Metabolism and Post-Transcriptional Gene Regulation provides a basis from which potential therapeutic strategies may be developed. This book will be of vital interest to cell and molecular biologists at all levels, from graduate students to senior investigators, clinical researchers, and professionals in the pharmaceutical and biotechnology industries. Author Biography Joe B. Harford and David R. Morris are the authors of mRNA Metabolism & Post-Transcriptional Gene Regulation, published by Wiley. Table of Contents Partial table of contents: RNA Structure (E. Puglisi & J. Puglisi). Transcription and Transcriptional Control: An Overview (I. Olave,et al.). Constitutive and Alternative mRNA Splicing (S. Bernstein & D.Hodges). mRNA Polyadenylation: Functional Implications (E. Baker). RNA Export from the Nucleus (L. Maquat). The Intracellular mRNA Sorting System: Postal Codes, Zip Codes,Mail Bags and Mail Boxes (O. Steward & R. Singer). The Fundamentals of Translation Initiation (H. Huang & T.Donahue). Mechanisms of mRNA Turnover in Eukaryotic Cells (S. Tharun & R.Parker). Control of mRNA Decay in Plants (A. van Hoof & P. Green). mRNA Metabolism and Cancer (M. Korth & M. Katze). Translational Regulation in Animal Virus-Infected Cells (R.Schneider). RNA Decay by the Interferon-Regulated 2-5A System as a Host DefenseAgainst Viruses (R. Silverman & N. Cirino). Control of mRNA Stability During Herpes Simplex Virus Infection (G.Read). Regulation of mRNA Expression in HIV-1 and Other Retroviruses (B.Felber). Index. Long Description mRNA METABOLISM & POST-TRANSCRIPTIONAL GENE REGULATION Edited by Joe B. Harford and David R. Morris Gene expression is a process that begins with the transcription of DNA to an RNA messenger (mRNA), which is then translated into a protein. Historically, attention has been focused on the regulation of RNA synthesis (transcription); however, there is a growing recognition of and appreciation for the importance of the many regulatory mechanisms that take place after RNA synthesis has been completed. mRNA Metabolism and Post-Transcriptional Gene Regulation is the first comprehensive overview of the various modes of gene regulation that exist post-transcriptionally. Collecting studies by some of the top researchers in the field, this volume provides both an up-to-date review of the complex "life" of an mRNA molecule and an introduction to current work on the diversity of mechanisms of post-transcriptional reactions. Topics covered include: RNA structure Mammalian RNA editing RNA export from the nucleus The fundamentals of translation initiation Control of mRNA decay in plants mRNA metabolism and cancer Control of mRNA stability during herpes simplex virus infection Regulation of mRNA expression in HIV-1 and other complex retroviruses Nucleases RNA localization A timely contribution to the understanding of genetic regulatory mechanisms, mRNA Metabolism and Post-Transcriptional Gene Regulation provides a basis from which potential therapeutic strategies may be developed. This book will be of vital interest to cell and molecular biologists at all levels, from graduate students to senior investigators, clinical researchers, and professionals in the pharmaceutical and biotechnology industries. Feature Provides a unique, comprehensive overview of this subject. Details ISBN0471142069 Author David R. Morris Series Modern Cell Biology Language English ISBN-10 0471142069 ISBN-13 9780471142065 Media Book Series Number 17 Year 1997 Place of Publication New York Country of Publication United States Edited by David R. Morris Illustrations Illustrations Edition 1st Format Paperback Short Title MRNA METABOLISM & POST-TRANSCR DOI 10.1604/9780471142065 UK Release Date 1997-04-07 AU Release Date 1997-04-07 NZ Release Date 1997-04-07 US Release Date 1997-04-07 Pages 368 Publisher John Wiley & Sons Inc Publication Date 1997-04-07 Imprint Wiley-Liss Inc.,U.S. DEWEY 572.88 Audience Undergraduate We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:102471188;

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