Innate and Adaptive Immunity in the Tumor Microenvironment by Eitan Yefenof (Eng

Description: Innate and Adaptive Immunity in the Tumor Microenvironment by Eitan Yefenof Cancer cells are continuously interacting with the immune system of the host. Traditionally, the interplay between cancer cells and host immunity has been studied systemically, with no particular attention to the site at which a given tumor develops. FORMAT Hardcover LANGUAGE English CONDITION Brand New Publisher Description Cancer cells are continuously interacting with the immune system of the host. These interactions can be regarded as a double edged sword. On the one hand, innate and adaptive immune responses act to protect the host by attempting rejection of the tumor. On the other hand, inflammatory cells and proteins stimulate multiplication and dissemination of cancer cells, thereby accelerating the progression of the disease. Traditionally, the interplay between cancer cells and host immunity has been studied systemically, with no particular attention to the site at which a given tumor develops. Recent studies, however, indicate that the tumor microenvironment is unique in providing both supportive and inhibitory factors that determine the fate of the tumor and its host. Accordingly, microenvironmental immunity that operates inside and around a tumor plays a crucial role in cancer development and progression. The aim of the present volume is to compile reviews on innate and adaptive immune responses at the tumor microenvironment with emphasis on positive and negative outcomes that affect the progression of the disease. These reviews have been solicited from experts in the field who published original research studies focusing on these issues. Notes Novel topic in bio-medical researchFundamental and practical issues related to cancer therapyOf interest to students, researchers and physicians Table of Contents Immune Effector Cells in the Tumor Microenvironment: Their Role in Regulation of Tumor Progression.- Histocompatibility Antigens, Tumor Microenvironment and Escape Mechanisms Utilized by Tumor Cells.- Local Tumor Growth and Spontaneous Systemic T Cell Responses in Cancer Patients: A Paradox and Puzzle.- Insights into Mechanisms of Immune Resistance in the Tumor Microenvironment through Molecular Profiling.- Tumor Antigens as Modulators of the Tumor Microenvironment.- Tumor Cell Resistance to Apoptosis by Infi ltrating Cytotoxic Lymphocytes.- The Tumor Microenvironment as a Model for Tissue-Specific Rejection.- Functional Cytotoxicity of T Cells in the Tumor Microenvironment.- Natural Killer Cells at the Tumors Microenvironment.- Contribution of the Microenvironment to the Pathogenesis of EBV-Positive Hodgkin and Nasal NK/T-cell Lymphomas. Long Description Cancer cells are continuously interacting with the immune system of the host. These interactions can be regarded as a double edged sword. On the one hand, innate and adaptive immune responses act to protect the host by attempting rejection of the tumor. On the other hand, inflammatory cells and proteins stimulate multiplication and dissemination of cancer cells, thereby accelerating the progression of the disease. Traditionally, the interplay between cancer cells and host immunity has been studied systemically, with no particular attention to the site at which a given tumor develops. Recent studies, however, indicate that the tumor microenvironment is unique in providing both supportive and inhibitory factors that determine the fate of the tumor and its host. Accordingly, microenvironmental immunity that operates inside and around a tumor plays a crucial role in cancer development and progression. The aim of the present volume is to compile reviews on innate and adaptive immune responses at the tumor microenvironment with emphasis on positive and negative outcomes that affect the progression of the disease. These reviews have been solicited from experts in the field who published original research studies focusing on these issues. Feature Novel topic in bio-medical research Fundamental and practical issues related to cancer therapy Of interest to students, researchers and physicians Details ISBN1402067496 Short Title INNATE & ADAPTIVE IMMUNITY IN Pages 212 Language English ISBN-10 1402067496 ISBN-13 9781402067495 Media Book Format Hardcover Series Number 1 Imprint Springer-Verlag New York Inc. Place of Publication New York, NY Country of Publication United States Edited by Eitan Yefenof Edition 2008th Illustrations XII, 212 p. AU Release Date 2007-12-04 NZ Release Date 2007-12-04 US Release Date 2007-12-04 UK Release Date 2007-12-04 Author Eitan Yefenof Publisher Springer-Verlag New York Inc. Edition Description 2008 ed. Series The Tumor Microenvironment Year 2007 Publication Date 2007-12-04 Alternative 9789048177134 DEWEY 616.99407 Audience Professional & Vocational We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:132335613;

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