EGFR-Directed Therapy in Lung Cancer by So Yeon Kim Paperback Book

Description: EGFR-Directed Therapy in Lung Cancer by So Yeon Kim, Daniel B. Costa, Daisuke Shibahara, Susumu Kobayashi, Balazs Halmos Estimated delivery 3-12 business days Format Paperback Condition Brand New Description This Element describes the structural biology and pathophysiology of EGFR-mutant NSCLC and describes past, current, and future treatment options in different settings. It discusses the biology and recently approved treatment for EGFR-exon 20 insertion mutation and the treatment for the uncommon mutations. Publisher Description Epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC) is a clinically important driver alteration affecting approximately one-third of lung cancer patients. Treatments for EGFR-exon 19 deletion and exon 21 L858R NSCLC have evolved over the last decade from first-generation reversible tyrosine kinase inhibitors (TKI) to third-generation irreversible TKIs, of which osimertinib has been the widely accepted as first-line therapy. Despite survival improvement seen with osimertinib and its efficacy against acquired T790M mutation, resistance through on-target and off-target pathways eventually develop. This Element describes the structural biology and pathophysiology of EGFR-mutant NSCLC and discusses past, current, and future treatment options in the metastatic, neoadjuvant, and adjuvant settings. It describes the biology and recently approved treatment for EGFR-exon 20 insertion mutation and the treatment for the uncommon exon 18 (G719X), 20 (S768I), and 21 (L861Q) mutations. It also outlines the promising clinical applications of circulating tumor DNA (ctDNA). Details ISBN 1009342304 ISBN-13 9781009342308 Title EGFR-Directed Therapy in Lung Cancer Author So Yeon Kim, Daniel B. Costa, Daisuke Shibahara, Susumu Kobayashi, Balazs Halmos Format Paperback Year 2023 Pages 75 Publisher Cambridge University Press GE_Item_ID:139636614; About Us Grand Eagle Retail is the ideal place for all your shopping needs! With fast shipping, low prices, friendly service and over 1,000,000 in stock items - you're bound to find what you want, at a price you'll love! Shipping & Delivery Times Shipping is FREE to any address in USA. Please view eBay estimated delivery times at the top of the listing. Deliveries are made by either USPS or Courier. We are unable to deliver faster than stated. International deliveries will take 1-6 weeks. NOTE: We are unable to offer combined shipping for multiple items purchased. This is because our items are shipped from different locations. Returns If you wish to return an item, please consult our Returns Policy as below: Please contact Customer Services and request "Return Authorisation" before you send your item back to us. Unauthorised returns will not be accepted. Returns must be postmarked within 4 business days of authorisation and must be in resellable condition. Returns are shipped at the customer's risk. We cannot take responsibility for items which are lost or damaged in transit. For purchases where a shipping charge was paid, there will be no refund of the original shipping charge. Additional Questions If you have any questions please feel free to Contact Us. Categories Baby Books Electronics Fashion Games Health & Beauty Home, Garden & Pets Movies Music Sports & Outdoors Toys

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