Cell Signaling, 2nd edition: Principles and Mechanisms by Bruce J. Mayer Paperba

Description: Cell Signaling, 2nd edition by Bruce J. Mayer, Wendell A. Lim This second edition presents the principles and components that underlie signaling processes. Intended for undergraduate and graduate students, the book aims to develop a broad conceptual framework through which students can make sense of the myriad pathways used by the cells to communicate. FORMAT Paperback CONDITION Brand New Publisher Description Cell Signaling provides undergraduate and graduate students with the conceptual tools needed to make sense of the dizzying array of pathways that cells use to detect, process, and respond to signals from the environment. By emphasizing the common design principles and molecular processes that underlie all signaling mechanisms, the book develops a broad conceptual framework through which students can understand diverse signaling pathways and networks. The book first examines the common currencies of cellular information processing and the core components of the signaling machinery. It then shows how these individual components link together into networks and pathways to perform more sophisticated tasks. Many specific examples are provided throughout to illustrate common principles, and to provide a comprehensive overview of major signaling pathways.Thoroughly revised, this second edition includes two new chapters and substantial updates to the text and figures throughout the book.Key features:The book provides a conceptual framework through which all signaling pathways can be understood without memorization of detailsIt is extensively illustrated, including high-quality diagrams and schematics to elucidate important concepts and processesEach chapter concludes with a useful summary section that brings together the key conceptsEnd-of-chapter review questions test the readers understanding of the material coveredTwo new chapters have been written especially for this edition: "Signaling and Disease" and "Diversity in Signaling across Phylogeny" Author Biography Wendell A. Lim is Professor of Cellular and Molecular Pharmacology at the University of California, San Francisco. The principal focus of his research is the structure and mechanism of protein interaction domains and the logic by which these components are used to build complex cellular signaling systems.Bruce J. Mayer is Professor of Genetics and Genome Sciences at the University of Connecticut, School of Medicine. Current work of his group focuses on characterizing and manipulating tyrosine kinase–mediated signal transduction pathways. Table of Contents 1. Introduction to Cell Signaling. 2. Principles and Mechanisms of Protein Interactions. 3. Signaling Enzymes and Their Allosteric Regulation. 4. Role of Post-Translational Modifications in Signaling. 5. Subcellular Localization of Signaling Molecules. 6. Second Messengers: Small Signaling Mediators. 7. Membranes, Lipids, and Enzymes that Modify Them. 8. Information Transfer Across the Membrane. 9. Regulated Protein Degradation. 10. The Modular Architecture and Evolution of Signaling Proteins. 11. Information Processing by Signaling Devices in Networks. 12. Signaling and Disease. 13. Diversity of Signaling Across Phylogeny 14. How Cells Make Decisions. 15. Methods for Studying Signaling Proteins and Networks. Details ISBN0367279371 Author Wendell A. Lim Edition Description 2nd edition Year 2024 Edition 2nd ISBN-13 9780367279370 Format Paperback Subtitle Principles and Mechanisms Alternative 9780367279424 Illustrations 13 Tables, color; 314 Line drawings, color; 56 Halftones, color; 370 Illustrations, color Audience Tertiary & Higher Education Publisher Taylor & Francis Ltd Place of Publication London Country of Publication United Kingdom Imprint CRC Press Replaces 9780815342441 DEWEY 571.74 ISBN-10 0367279371 Pages 441 Publication Date 2024-10-30 UK Release Date 2024-10-30 We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:151335259;

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