Description: Aquaporins by Baoxue Yang This book provides a state-of-the-art report on our current understanding of aquaporins and the future direction of the field. Aquaporins (AQPs) are a group of water-channel proteins that are specifically permeable to water and other small molecules, such as glycerol and urea. To date thirteen water-channel proteins (AQP0 – AQP12) have been cloned and the mechanisms and physiological functions of water transport across biological membranes have long been the subject of interest. Recent advances in the molecular biology and physiology of water transport have yielded new insights into how and why water moves across cell membranes, and studies on aquaporin knockout mouse models suggest that aquaporins are involved in the development of some diseases and they may be useful targets of research into selective-inhibitor drugs. By focusing on the advances made over the last 30 years in the biophysics, genetics, protein structure, molecular biology, physiology, pathophysiology and pharmacology of aquaporins in mammalian cell membranes, this book provides novel insights into further mechanisms and the physiological significance of water and some small molecule transport in mammals in order to stimulate further research in new directions.In the second version, fourteen chapters will be updated base on the most recent research articles. Ten new chapters will be added. FORMAT Hardcover LANGUAGE English CONDITION Brand New Back Cover This book provides a state-of-the-art report on our current understanding of aquaporins and the future direction of the field. Aquaporins (AQPs) are a group of water-channel proteins that are specifically permeable to water and other small molecules, such as glycerol and urea. To date thirteen water-channel proteins (AQP0 - AQP12) have been cloned and the mechanisms and physiological functions of water transport across biological membranes have long been the subject of interest. Recent advances in the molecular biology and physiology of water transport have yielded new insights into how and why water moves across cell membranes, and studies on aquaporin knockout mouse models suggest that aquaporins are involved in the development of some diseases and they may be useful targets of research into selective-inhibitor drugs. By focusing on the advances made over the last 30 years in the biophysics, genetics, protein structure, molecular biology, physiology, pathophysiology and pharmacology of aquaporins in mammalian cell membranes, this book provides novel insights into further mechanisms and the physiological significance of water and some small molecule transport in mammals in order to stimulate further research in new directions. In the second version, fourteen chapters will be updated base on the most recent research articles. Ten new chapters will be added. Author Biography Baoxue Yang is a professor and chairman of Department of Pharmacology at Peking University. Prof. Yang has been studying aquaporins for nearly 27 years and published more than 100 original research articles in related fields. Table of Contents 1. Classification and Gene Structure of Aquaporins.- 2. Protein Structure and Modification of Aquaporins.- 3. Expression Regulation and Trafficking of Aquaporins.- 4. Transport Characteristics of Aquaporins.- 5. Non-transport Functions of Aquaporins.- 6. The Evolutionary Aspects of Aquaporin Superfamily.- 7. Aquaporins in Nervous System.- 8. Aquaporins in Cardiovascular System.- 9. Aquaporins in Respiratory System.- 10. Aquaporins in Digestive System.- 11. Aquaporins in Urinary System.- 12. Aquaporins in Reproductive System.- 13. Aquaporins in Immune System.-14. Aquaporins in Eye.- 15. Aquaporins in Skin.- 16. Aquaporins in Glandular Secretion.- 17. Aquaporins in Fetal Development.- 18. Aquaporins in Diabetes Insipidus.- 19. Aquaporins in Edema.- 20. Aquaporins in Obesity.-21. Aquaporins in Tumor.- 22. Aquaporin Inhibitors.- 23. Non-aquaporin Water Channels.-24. Methods to Measure Water Permeability. Feature Provides a state-of-the-art on recent developments and future directions in aquaporin research Provides a systematic and comprehensive overview into aquaporins Covers diverse aspects of aquaporin research Details ISBN9811974144 Series Advances in Experimental Medicine and Biology Language English Edition 2nd ISBN-10 9811974144 ISBN-13 9789811974144 Format Hardcover DOI 10.1007/978-981-19-7415-1 DEWEY 572.696 Series Number 1398 Year 2023 Publisher Springer Verlag, Singapore Imprint Springer Verlag, Singapore Place of Publication Singapore Country of Publication Singapore Author Baoxue Yang Pages 365 Publication Date 2023-01-31 Edited by Baoxue Yang Illustrations 1 Illustrations, black and white; VIII, 365 p. 1 illus. UK Release Date 2023-01-31 Edition Description 2nd ed. 2023 Replaces 9789402410556 Alternative 9789811974175 Audience Professional & Vocational We've got this At The Nile, if you're looking for it, we've got it. 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Book Title: Aquaporins
